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  • Anti-HSP70 Monoclonal Antibody
產(chǎn)品名稱：

Anti-HSP70 Monoclonal Antibody
產(chǎn)品品牌： SOLARBIO/索萊寶 價格：
廠商性質(zhì)： 生產(chǎn)廠家 產(chǎn)品時間： 2022-08-15
Anti-HSP70 Monoclonal Antibody
應用 WB IF
稀釋比例WB 1:1000-2000. IF 1:100-200.
交叉反應Human Mouse Rat

產(chǎn)品概述

品牌SOLARBIO/索萊寶貨號K200048M
規(guī)格50ul/100ul供貨周期現(xiàn)貨
主要用途WB IF應用領域醫(yī)療衛(wèi)生,環(huán)保,化工,生物產(chǎn)業(yè),農(nóng)林牧漁

Anti-HSP70 Monoclonal Antibody

英文名稱Anti-HSP70 Monoclonal Antibody
宿主Mouse
別名heat shock protein 70
應用WB IF
稀釋比例WB 1:1000-2000. IF 1:100-200.
交叉反應Human Mouse Rat
蛋白分子量70kDa
Gene ID3303/3304
保存Store at -20°C. Avoid freeze / thaw cycles.
儲存液Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
純化方法Affinity purification
亞型IgG1
免疫原A synthetic peptide coupled to KLH
性狀液體
Public Immunogen Range

A synthetic peptide coupled to KLH

Subcellular LocationsCytoplasm
Swiss ProtP0DMV8/P0DMV9
克隆號3G10
克隆類型Monoclonal Antibody
背景資料The 70 kilodalton heat shock proteins (Hsp70s) are a family of ubiquitously expressed heat shock proteins. Proteins with similar structure exist in virtually all living organisms. The Hsp70s are an important part of the cell's machinery for protein folding, and help to protect cells from stress. Hsp70 is usually in an ATP bound state. Hsp70 by itself is characterized by a very weak ATPase activity, such that spontaneous hydrolysis will not occur for many minutes. As newly synthesized proteins emerge from the ribosomes, the substrate binding domain of Hsp70 recognizes sequences of hydrophobic amino acid residues, and interacts with them. This spontaneous interaction is reversible, and in the ATP bound state Hsp70 may relatively freely bind and release peptides. However, the presence of a peptide in the binding domain stimulates the ATPase activity of Hsp70, increasing its normally slow rate of ATP hydrolysis.

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