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  • Anti-RUNX2 Polyclonal Antibody
產(chǎn)品名稱：

Anti-RUNX2 Polyclonal Antibody
產(chǎn)品品牌： SOLARBIO/索萊寶 價(jià)格：
廠商性質(zhì)： 生產(chǎn)廠家 產(chǎn)品時(shí)間： 2022-08-15
Anti-RUNX2 Polyclonal Antibody
應(yīng)用 WB
稀釋比例WB 1:500-2000.
交叉反應(yīng)Human Mouse

產(chǎn)品概述

品牌SOLARBIO/索萊寶貨號(hào)K101309P
規(guī)格50ul/100ul供貨周期現(xiàn)貨
主要用途WB應(yīng)用領(lǐng)域醫(yī)療衛(wèi)生,環(huán)保,化工,生物產(chǎn)業(yè),農(nóng)林牧漁

Anti-RUNX2 Polyclonal Antibody

英文名稱Anti-RUNX2 Polyclonal Antibody
宿主Rabbit
別名AML3;CBF-alpha-1;CBFA1;CCD;CCD1;CLCD;OSF-2;OSF2;PEA2aA;PEBP2aA
應(yīng)用WB
稀釋比例WB 1:500-2000.
交叉反應(yīng)Human Mouse
蛋白分子量56kDa
Gene ID860
保存Store at -20°C. Avoid freeze / thaw cycles.
儲(chǔ)存液Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
純化方法Affinity purification
亞型IgG
免疫原A synthetic peptide of human RUNX2
性狀液體
Public Immunogen RangeA synthetic peptide of human RUNX2
Subcellular LocationsNucleus
Swiss ProtQ13950
克隆類型Polyclonal Antibody
背景資料Transcription factor involved in osteoblastic differentiation and skeletal morphogenesis. Essential for the maturation of osteoblasts and both intramembranous and endochondral ossification. CBF binds to the core site, 5'-PYGPYGGT-3', of a number of enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers, osteocalcin, osteopontin, bone sialoprotein, alpha 1(I) collagen, LCK, IL-3 and GM-CSF promoters. In osteoblasts, supports transcription activation: synergizes with SPEN/MINT to enhance FGFR2-mediated activation of the osteocalcin FGF-responsive element (OCFRE) (By similarity). Inhibits KAT6B-dependent transcriptional activation.

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