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  • Anti-IL12 Polyclonal Antibody
產(chǎn)品名稱：

Anti-IL12 Polyclonal Antibody
產(chǎn)品品牌： SOLARBIO/索萊寶 價格：
廠商性質(zhì)： 生產(chǎn)廠家 產(chǎn)品時間： 2022-08-15
Anti-IL12 Polyclonal Antibody
應(yīng)用 WB
稀釋比例WB 1:3000.
交叉反應(yīng)Human Mouse Rat

產(chǎn)品概述

品牌SOLARBIO/索萊寶貨號K106473P
規(guī)格50ul/100ul供貨周期現(xiàn)貨
主要用途WB應(yīng)用領(lǐng)域醫(yī)療衛(wèi)生,環(huán)保,化工,生物產(chǎn)業(yè),農(nóng)林牧漁

Anti-IL12 Polyclonal Antibody

英文名稱Anti-IL12 Polyclonal Antibody
宿主Rabbit
別名IL-12A;CLMF p35;IL-12 subunit p35;NKSF1;IL12A
應(yīng)用WB
稀釋比例WB 1:3000.
交叉反應(yīng)Human Mouse Rat
蛋白分子量52kDa
Gene ID3592
保存Store at -20°C. Avoid freeze / thaw cycles.
儲存液Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
純化方法Affinity purification
亞型IgG
免疫原A synthetic peptide of human IL12
性狀液體
Public Immunogen RangeA synthetic peptide of human IL12
Subcellular LocationsCell membrane Secreted
Swiss ProtP29459
克隆類型Polyclonal Antibody
背景資料IL-12 protein is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract.

 

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