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        您的位置: 網(wǎng)站首頁(yè) > 產(chǎn)品中心 > 生化試劑 > 胺、酸和鹽 > S8320(胺鹽)Spermidine trihydrochloride
        • (胺鹽)Spermidine trihydrochloride
        • (胺鹽)Spermidine trihydrochloride
        • (胺鹽)Spermidine trihydrochloride
        • (胺鹽)Spermidine trihydrochloride
        產(chǎn)品名稱:

        (胺鹽)Spermidine trihydrochloride

        產(chǎn)品品牌: SOLARBIO/索萊寶 價(jià)格:
        廠商性質(zhì): 生產(chǎn)廠家 產(chǎn)品時(shí)間: 2024-07-09
        (胺鹽)Spermidine trihydrochloride
        貨號(hào):S8320
        規(guī)格:1g
        用途:抑制神經(jīng)元氧化一氮合成酶(nNOS)活性;能與DNA結(jié)合沉淀DNA,被用于與蛋白質(zhì)相結(jié)合的DNA的純化;刺激T4多聚核苷酸激酶的活性。

        產(chǎn)品概述

        品牌SOLARBIO/索萊寶

         

         

        (胺鹽)Spermidine trihydrochloride

        產(chǎn)品編號(hào)規(guī) 格
        S8320-1 1g 


        說(shuō)明:抑制神經(jīng)元氧化一氮合成酶(nNOS)活性;能與DNA結(jié)合沉淀DNA,被用于與蛋白質(zhì)相結(jié)合的DNA的純化;刺激T4多聚核苷酸激酶的活性。


        別名:三鹽酸精脒; N,-(3-氨基丙基)-1,4-丁二胺 三鹽酸鹽;
        鹽酸精脒;Spermidine hydrochloride;N,- (3-Aminopropyl)butane-1,4-diamine hydrochloride


        分子式:C 7 H 19 N 3 ·3HCl 分子量:254.63


        C A S #:334-50-9


        外觀:無(wú)色或白色結(jié)晶


        特性:純度(%):≥98(TLC)


        溶解性:溶于水, 熔點(diǎn):257-259 ℃


        R:36/37/38 S:26-36


        儲(chǔ)存條件: −20℃

         

        (胺鹽)Spermidine trihydrochloride結(jié)構(gòu)式:

        Spermidine trihydrochloride

        Storage Temperature 2-8 °C
        Product Description
        Molecular Formula: C 7 H 19 N 3
        Molecular Weight: 145.2
        CAS Number: 124-20-9
        Melting Point: 23-25 °C
        Density: 0.925 g/ml
        Refractive Index: 1.4790 (20 °C)
        This product is suitable for molecular biology applications. DNase, RNase, or protease activities were not detected.
        Spermidine is biogenic polyamine formed from putrescine, a precursor of spermine. It was first detected in human sperm, but occurs widely in nature.
        It is essential in both normal and neoplastic tissue growth.

        1Spermidine has a role in cell growth processes 

         

        2 and the formation and interconversion of spermidine in mammalian cells has been reported.

        3It has been studied in the regulation of tRNA methyltransferase activity

        4and stimulates T4 polynucleotide kinase activity.

        5 Precautions and Disclaimer
        For Laboratory Use Only. Not for drug, household or other uses.
        Preparation Instructions Spermidine is soluble in water (50 mg/ml), ethanol,
        and ether.

        6Storage/Stability Spermidine is very hygroscopic and air sensitive.


        A solution can be formed for storage by dissolving 1.45 g in 10 ml of water and then sterilizing with a 0.22 μm filter. Store this solution as single-use aliquots at ?20 °C for no more than one month.

        7 Spermidine free base should be sterile-filtered and not autoclaved, if a sterile solution is necessary. 

        References
        1. The Index, 11th ed., Entry# 8698.


        2. Janne, J., et al., Polyamines in Rapid Growth and Cancer. Biochim. Biophys. Acta, 473(3-4), 241-293 (1978).


        3. Porter, C. W., and Bergeron, R. J., Spermidine Requirement for Cell Proliferation in Eukaryotic
        Cells: Structural Specificity and Quantitation.
        Science, 219(4588), 1083-1085 (1983).


        4. Pegg, A. E., et al., Formation and Interconversion of Putrescine and Spermidine in Mammalian Cells. Adv. Enzyme Regul., 19, 427-451 (1980).


        5. Mach, M., et al., Regulation of tRNA Methyltransferase Activities by Spermidine and Putrescine. Inhibition of Polyamine Synthesis and tRNA Methylation by Alpha-methylornithine or 1,3-diaminopropan-2-ol in Dictyosium. Biochem. J.,
        202(1), 153-162 (1982).


        6. Molecular Cloning: A Laboratory Manual, 3rd ed.,
        Sambrook, J. F., et al., Cold Spring Harbor
        Laboratory Press (Cold Spring Harbor, NY: 2001),
        p. A.435.


        7. Molecular Cloning: A Laboratory Manual, 3rd ed.,
        Sambrook, J. F., et al., Cold Spring Harbor
        Laboratory Press (Cold Spring Harbor, NY: 2001),
        p. A1.28.
        JSX/ARO/RXR 2/04

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